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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | P2X purinoceptor 3 | ||
| Ligand | BDBM266762 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Human P2X3 Receptor Inhibition Assay | ||
| pH | 7.5±n/a | ||
| IC50 | 1.000±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| P2X purinoceptor 3 | |||
| Name: | P2X purinoceptor 3 | ||
| Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa | ||
| Type: | Protein | ||
| Mol. Mass.: | 44292.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P56373 | ||
| Residue: | 397 | ||
| Sequence: |
| ||
| BDBM266762 | |||
| n/a | |||
| Name | BDBM266762 | ||
| Synonyms: | US9718790, I-2497 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H30N6O4 | ||
| Mol. Mass. | 478.5435 | ||
| SMILES | CCn1c(=O)[nH]\c(=N/c2ccc(Oc3cccc(n3)C(N)=O)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:26.27,wD:29.31,(7.34,,;6,.77,;4.67,,;3.33,.77,;3.33,2.31,;2,,;2,-1.54,;.67,-2.31,;-.67,-1.54,;-.67,,;-2,.77,;-3.33,,;-4.67,.77,;-4.67,2.31,;-3.33,3.08,;-3.33,4.62,;-4.67,5.39,;-6,4.62,;-6,3.08,;-7.34,5.39,;-8.67,4.62,;-7.34,6.93,;-3.33,-1.54,;-2,-2.31,;3.33,-2.31,;3.33,-3.85,;4.67,-4.62,;6,-3.85,;7.34,-4.62,;7.34,-6.16,;8.67,-6.93,;6,-6.93,;4.67,-6.16,;4.67,-1.54,;6,-2.31,)| | ||
| Structure | 
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