| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 3 |
|---|
| Ligand | BDBM266400 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Rat P2X3 Receptor Inhibition Assay |
|---|
| pH | 7.5±n/a |
|---|
| IC50 | 19.0±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 3 |
|---|
| Name: | P2X purinoceptor 3 |
|---|
| Synonyms: | ATP receptor | P2RX3_RAT | P2X purinoceptor 3 | P2X3 | P2rx3 | Purinergic receptor | ratp2x3 | ratp2x3 + rsa |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44397.63 |
|---|
| Organism: | RAT |
|---|
| Description: | Purinergic, P2X3 0 RAT::P49654 |
|---|
| Residue: | 397 |
|---|
| Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDS
QCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEE
VTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
|
|
|
|---|
| BDBM266400 |
|---|
| n/a |
|---|
| Name | BDBM266400 |
|---|
| Synonyms: | US9718790, I-0837 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H25ClN4O5 |
|---|
| Mol. Mass. | 484.932 |
|---|
| SMILES | C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(OCC3CC3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
