| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM31735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors |
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| IC50 | 4400±200 nM |
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| Citation |  PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM31735 |
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| n/a |
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| Name | BDBM31735 |
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| Synonyms: | (7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-(2-furanylmethylidene)-8-thiazolo[4,5]imidazo[1,2-b]pyridinone | (7Z)-3-bromo-7-(2-furfurylidene)thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-(furan-2-ylmethylidene)-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | MLS-0091940.0001 | cid_6456506 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H6BrN3O2S |
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| Mol. Mass. | 348.175 |
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| SMILES | Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21 |
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| Structure | 
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