| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM31753 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors |
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| IC50 | 5100±100 nM |
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| Citation |  PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM31753 |
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| n/a |
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| Name | BDBM31753 |
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| Synonyms: | MLS-0067138.0001 | cid_16654632 | disodium;(7E)-8-keto-7-[(6-sulfonato-2-naphthyl)hydrazono]quinoline-5-sulfonate | disodium;(7E)-8-oxidanylidene-7-[(6-sulfonatonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonate | disodium;(7E)-8-oxo-7-[(6-sulfonato-2-naphthalenyl)hydrazinylidene]-5-quinolinesulfonate | disodium;(7E)-8-oxo-7-[(6-sulfonatonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H11N3O7S2 |
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| Mol. Mass. | 457.438 |
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| SMILES | Oc1c(cc(c2cccnc12)S([O-])(=O)=O)N=Nc1ccc2cc(ccc2c1)S([O-])(=O)=O |w:16.18| |
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| Structure | 
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