| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
|---|
| Ligand | BDBM31755 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors |
|---|
| IC50 | 23900±1300 nM |
|---|
| Citation |  PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Dual specificity protein phosphatase 6 |
|---|
| Name: | Dual specificity protein phosphatase 6 |
|---|
| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42303.19 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | gi_16758752 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
|
|
|
|---|
| BDBM31755 |
|---|
| n/a |
|---|
| Name | BDBM31755 |
|---|
| Synonyms: | 3-(benzylthio)-5,6-bis(2-furyl)-1,2,4-triazine | 3-benzylsulfanyl-5,6-bis(furan-2-yl)-1,2,4-triazine | 5,6-bis(2-furanyl)-3-(phenylmethylthio)-1,2,4-triazine | 5,6-bis(furan-2-yl)-3-(phenylmethylsulfanyl)-1,2,4-triazine | MLS-0029114.0001 | cid_2940938 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H13N3O2S |
|---|
| Mol. Mass. | 335.38 |
|---|
| SMILES | C(Sc1nnc(-c2ccco2)c(n1)-c1ccco1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
