| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mothers against decapentaplegic homolog 3 |
|---|
| Ligand | BDBM41962 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation |
|---|
| IC50 | 3276.961399±n/a nM |
|---|
| Citation |  PubChem, PC SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mothers against decapentaplegic homolog 3 |
|---|
| Name: | Mothers against decapentaplegic homolog 3 |
|---|
| Synonyms: | MADH3 | SMAD3 | SMAD3_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48085.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5174513 |
|---|
| Residue: | 425 |
|---|
| Sequence: | MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS
|
|
|
|---|
| BDBM41962 |
|---|
| n/a |
|---|
| Name | BDBM41962 |
|---|
| Synonyms: | 2-[(Z)-(3,4-dihydroxyphenyl)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]besylic acid | 2-[(Z)-(3,4-dihydroxyphenyl)-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]benzenesulfonic acid | 2-[(Z)-(3,4-dihydroxyphenyl)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonic acid | 2-[(Z)-[3,4-bis(oxidanyl)phenyl]-(3-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonic acid | TG2-222-3 | cid_6150402 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H14O7S |
|---|
| Mol. Mass. | 386.375 |
|---|
| SMILES | Oc1ccc(cc1O)C(=C1CC(=O)C(=O)C=C1)c1ccccc1S(O)(=O)=O |w:8.18,c:16| |
|---|
| Structure | 
|
|---|
Search and Browse
