| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
|---|
| Ligand | BDBM34184 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study |
|---|
| IC50 | 1690±50 nM |
|---|
| Citation |  PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Bcl-2-related protein A1 |
|---|
| Name: | Bcl-2-related protein A1 |
|---|
| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
|---|
| Type: | Apoptosis regulator protein |
|---|
| Mol. Mass.: | 19909.74 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | gi_11024684 |
|---|
| Residue: | 172 |
|---|
| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
|
|
|
|---|
| BDBM34184 |
|---|
| n/a |
|---|
| Name | BDBM34184 |
|---|
| Synonyms: | MLS000052391 | N-[1-(1-adamantyl)-1H-pyrazol-4-yl]-5-(2-furyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | N-[1-(1-adamantyl)-4-pyrazolyl]-5-(2-furanyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide | N-[1-(1-adamantyl)pyrazol-4-yl]-5-(2-furyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | N-[1-(1-adamantyl)pyrazol-4-yl]-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | SMR000081749 | cid_2976134 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H23F3N6O2 |
|---|
| Mol. Mass. | 496.4843 |
|---|
| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)n1cc(NC(=O)c2cnn3c(cc(nc23)-c2ccco2)C(F)(F)F)cn1 |TLB:5:3:11:6.9.8,8:6:12:1.11.2,8:1:12:6.9.5,THB:5:6:11:3.12.2| |
|---|
| Structure | 
|
|---|
Search and Browse
