Ki Summary

Reaction Details

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Target

G2/mitotic-specific cyclin-B1

Ligand

BDBM38959

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation

EC50

>49750±n/a nM

Citation

PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G2/mitotic-specific cyclin-B1

Name:

G2/mitotic-specific cyclin-B1

Synonyms:

CCNB | CCNB1 | CCNB1_HUMAN

Type:

Enzyme Subunit

Mol. Mass.:

48340.95

Organism:

Homo sapiens (Human)

Description:

P14635

Residue:

433

Sequence:

MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV

BDBM38959

n/a

Name

BDBM38959

Synonyms:

4-(1-methyl-2-oxidanylidene-quinolin-4-yl)oxy-N-(4-methylpyridin-2-yl)butanamide | 4-(1-methyl-2-oxoquinolin-4-yl)oxy-N-(4-methylpyridin-2-yl)butanamide | 4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide | 4-[(1-methyl-2-oxo-4-quinolinyl)oxy]-N-(4-methyl-2-pyridinyl)butanamide | 4-[(2-keto-1-methyl-4-quinolyl)oxy]-N-(4-methyl-2-pyridyl)butyramide | MLS000089581 | SMR000027929 | cid_3237904

Type

Small organic molecule

Emp. Form.

C20H21N3O3

Mol. Mass.

351.399

SMILES

Cc1ccnc(NC(=O)CCCOc2cc(=O)n(C)c3ccccc23)c1

Structure