| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
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| Ligand | BDBM43755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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| EC50 | >49750±n/a nM |
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| Citation |  PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| G2/mitotic-specific cyclin-B1 |
|---|
| Name: | G2/mitotic-specific cyclin-B1 |
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| Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48340.95 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | P14635 |
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| Residue: | 433 |
|---|
| Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
|
|
|
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| BDBM43755 |
|---|
| n/a |
|---|
| Name | BDBM43755 |
|---|
| Synonyms: | 3-hydroxy-7-phenyl-pyrrolo[3,2-e][2,1,3]benzoxadiazole | 3-hydroxy-7-phenylpyrrolo[3,2-e][2,1,3]benzoxadiazole | 3-oxidanyl-7-phenyl-pyrrolo[3,2-e][2,1,3]benzoxadiazole | 7-phenyl-6H-[1,2,5]oxadiazolo[3,4-e]indole 3-oxide | MLS000061388 | SMR000069284 | cid_690911 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C14H9N3O2 |
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| Mol. Mass. | 251.2402 |
|---|
| SMILES | On1onc2c1ccc1nc(cc21)-c1ccccc1 |
|---|
| Structure | 
|
|---|
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