| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
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| Ligand | BDBM43757 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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| EC50 | >49750±n/a nM |
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| Citation |  PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| G2/mitotic-specific cyclin-B1 |
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| Name: | G2/mitotic-specific cyclin-B1 |
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| Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48340.95 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | P14635 |
|---|
| Residue: | 433 |
|---|
| Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
|
|
|
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| BDBM43757 |
|---|
| n/a |
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| Name | BDBM43757 |
|---|
| Synonyms: | 2-furanyl-(8-methyl-2-sulfanylidene-[1,2,4]triazolo[1,5-a]pyridin-3-yl)methanone | 2-furyl-(8-methyl-2-thioxo-[1,2,4]triazolo[1,5-a]pyridin-3-yl)methanone | Furan-2-yl-(8-methyl-2-thioxo-2H-[1,2,4]triazolo[1,5-a]pyridin-3-yl)-methanone | MLS000554170 | SMR000146487 | cid_705546 | furan-2-yl-(8-methyl-2-sulfanylidene-[1,2,4]triazolo[1,5-a]pyridin-3-yl)methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9N3O2S |
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| Mol. Mass. | 259.284 |
|---|
| SMILES | Cc1cccn2n(C(=O)c3ccco3)c(=S)nc12 |
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| Structure | 
|
|---|
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