| Reaction Details |
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 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
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| Ligand | BDBM43763 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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| EC50 | >49750±n/a nM |
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| Citation |  PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| G2/mitotic-specific cyclin-B1 |
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| Name: | G2/mitotic-specific cyclin-B1 |
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| Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48340.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14635 |
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| Residue: | 433 |
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| Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
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|
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| BDBM43763 |
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| n/a |
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| Name | BDBM43763 |
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| Synonyms: | 4,5-Dimethoxy-1H-indole-2-carboxylic acid [1-(2,3-dimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide | MLS000332076 | N-[(2,3-dimethoxybenzylidene)amino]-4,5-dimethoxy-1H-indole-2-carboxamide | N-[(2,3-dimethoxyphenyl)methylideneamino]-4,5-dimethoxy-1H-indole-2-carboxamide | SMR000221624 | cid_1963601 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O5 |
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| Mol. Mass. | 383.3978 |
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| SMILES | COc1cccc(C=NNC(=O)c2cc3c(OC)c(OC)ccc3[nH]2)c1OC |w:8.8| |
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| Structure | 
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