| Reaction Details |
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 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
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| Ligand | BDBM43776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation |
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| EC50 | >5527±n/a nM |
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| Citation |  PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| G2/mitotic-specific cyclin-B1 |
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| Name: | G2/mitotic-specific cyclin-B1 |
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| Synonyms: | CCNB | CCNB1 | CCNB1_HUMAN |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48340.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14635 |
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| Residue: | 433 |
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| Sequence: | MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV
|
|
|
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| BDBM43776 |
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| n/a |
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| Name | BDBM43776 |
|---|
| Synonyms: | (5Z)-2-anilino-5-[(1-methyl-2-pyrrolyl)methylidene]-4-thiazolone | (5Z)-2-anilino-5-[(1-methylpyrrol-2-yl)methylene]-2-thiazolin-4-one | (5Z)-2-anilino-5-[(1-methylpyrrol-2-yl)methylidene]-1,3-thiazol-4-one | (5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-2-phenylazanyl-1,3-thiazol-4-one | 5-[1-(1-Methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-[(E)-phenylimino]-thiazolidin-4-one | MLS000333177 | SMR000436531 | cid_941925 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13N3OS |
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| Mol. Mass. | 283.348 |
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| SMILES | Cn1cccc1C=C1SC(Nc2ccccc2)=NC1=O |w:6.6,c:18| |
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| Structure | 
|
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