Ki Summary

Reaction Details

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Target

G2/mitotic-specific cyclin-B1

Ligand

BDBM43778

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation

EC50

>49750±n/a nM

Citation

PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G2/mitotic-specific cyclin-B1

Name:

G2/mitotic-specific cyclin-B1

Synonyms:

CCNB | CCNB1 | CCNB1_HUMAN

Type:

Enzyme Subunit

Mol. Mass.:

48340.95

Organism:

Homo sapiens (Human)

Description:

P14635

Residue:

433

Sequence:

MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
ALVQDLAKAVAKV

BDBM43778

n/a

Name

BDBM43778

Synonyms:

2-[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]sulfanyl-N-(phenylmethyl)ethanamide | 2-[[4-(3,4-dimethyl-5-thieno[2,3-b]thiophenyl)-2-pyrimidinyl]thio]-N-(phenylmethyl)acetamide | MLS000860689 | N-benzyl-2-[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]sulfanylacetamide | N-benzyl-2-[[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]thio]acetamide | N1-benzyl-2-{[4-(3,4-dimethylthieno[2,3-b]thiophen-2-yl)pyrimidin-2-yl]thio}acetamide | SMR000459473 | cid_2820576

Type

Small organic molecule

Emp. Form.

C21H19N3OS3

Mol. Mass.

425.59

SMILES

Cc1csc2sc(c(C)c12)-c1ccnc(SCC(=O)NCc2ccccc2)n1

Structure