| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphotransferase |
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| Ligand | BDBM43829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Temperature | 298.15±0 K |
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| Ki | 1.00e+5± 1e+3 nM |
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| IC50 | 6000000±0.0 nM |
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| Citation |  Willson, M; Sanejouand, YH; Perie, J; Hannaert, V; Opperdoes, F Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase. Chem Biol9:839-47 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Phosphotransferase |
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| Name: | Phosphotransferase |
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| Synonyms: | Hexokinase |
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| Type: | Protein |
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| Mol. Mass.: | 51306.14 |
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| Organism: | Trypanosoma brucei |
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| Description: | Q38C42 |
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| Residue: | 471 |
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| Sequence: | MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
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| BDBM43829 |
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| n/a |
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| Name | BDBM43829 |
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| Synonyms: | Glucosamine derivative, 2 | MLS000568543 | SMR000154737 | [4-(2-hydroxyphenyl)-1-piperazinyl]-(2-quinolinyl)methanone | [4-(2-hydroxyphenyl)piperazin-1-yl]-quinolin-2-yl-methanone | [4-(2-hydroxyphenyl)piperazin-1-yl]-quinolin-2-ylmethanone | [4-(2-hydroxyphenyl)piperazino]-(2-quinolyl)methanone | cid_2454966 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O2 |
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| Mol. Mass. | 333.3838 |
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| SMILES | Oc1ccccc1N1CCN(CC1)C(=O)c1ccc2ccccc2n1 |
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| Structure | 
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