| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphotransferase |
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| Ligand | BDBM43830 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Temperature | 298.15±0 K |
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| Ki | 1.05e+5± 2e+3 nM |
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| IC50 | 4500000±0.0 nM |
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| Citation |  Willson, M; Sanejouand, YH; Perie, J; Hannaert, V; Opperdoes, F Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase. Chem Biol9:839-47 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Phosphotransferase |
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| Name: | Phosphotransferase |
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| Synonyms: | Hexokinase |
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| Type: | Protein |
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| Mol. Mass.: | 51306.14 |
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| Organism: | Trypanosoma brucei |
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| Description: | Q38C42 |
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| Residue: | 471 |
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| Sequence: | MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
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| BDBM43830 |
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| n/a |
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| Name | BDBM43830 |
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| Synonyms: | 5-(amoxymethyl)-3-[2-[(4-phenylthiazol-2-yl)hydrazono]propyl]tetrahydrofuran-2-one | 5-(pentoxymethyl)-3-[2-[(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]propyl]oxolan-2-one | 5-(pentoxymethyl)-3-[2-[(4-phenyl-2-thiazolyl)hydrazinylidene]propyl]-2-oxolanone | 5-Pentyloxymethyl-3-{2-[(4-phenyl-thiazol-2-yl)-hydrazono]-propyl}-dihydro-furan-2-one | Glucosamine derivative, 3 | MLS000557649 | SMR000174499 | cid_2865032 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29N3O3S |
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| Mol. Mass. | 415.549 |
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| SMILES | CCCCCOCC1CC(CC(C)N=Nc2nc(cs2)-c2ccccc2)C(=O)O1 |w:13.12| |
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| Structure | 
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