| Reaction Details |
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 | Report a problem with these data |
| Target | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Ligand | BDBM43856 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 8.8e+4±n/a nM |
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| Citation |  Sogabe, S; Masubuchi, M; Sakata, K; Fukami, TA; Morikami, K; Shiratori, Y; Ebiike, H; Kawasaki, K; Aoki, Y; Shimma, N; D'Arcy, A; Winkler, FK; Banner, DW; Ohtsuka, T Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors. Chem Biol9:1119-28 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycylpeptide N-tetradecanoyltransferase 1 |
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| Name: | Glycylpeptide N-tetradecanoyltransferase 1 |
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| Synonyms: | Myristoyl-CoA:protein N-myristoyltransferase (Nmt) | N-myristoyltransferase (NMT1) | NMT | NMT1 | NMT1_HUMAN | Peptide N-myristoyltransferase | Peptide N-myristoyltransferase 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 56814.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30419 |
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| Residue: | 496 |
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| Sequence: | MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK
QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW
DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY
VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK
KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS
LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF
HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY
SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN
WKCPSMGAEKVGLVLQ
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| BDBM43856 |
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| n/a |
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| Name | BDBM43856 |
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| Synonyms: | 4-ethoxy-N-[(6-fluoro-1,1-diketo-2,3-dihydrothiochromen-4-ylidene)amino]benzenesulfonamide | 4-ethoxy-N-[(6-fluoro-1,1-dioxo-2,3-dihydro-1-benzothiopyran-4-ylidene)amino]benzenesulfonamide | 4-ethoxy-N-[(6-fluoro-1,1-dioxo-2,3-dihydrothiochromen-4-ylidene)amino]benzenesulfonamide | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxidanylidene)-2,3-dihydrothiochromen-4-ylidene]amino]benzenesulfonamide | MLS000761277 | Non peptidic, 3 | SMR000369580 | cid_3596078 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17FN2O5S2 |
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| Mol. Mass. | 412.456 |
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| SMILES | CCOc1ccc(cc1)S(=O)(=O)NN=C1CCS(=O)(=O)c2ccc(F)cc12 |w:13.13| |
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| Structure | 
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