| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM44252 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist Activity against Muscarinic Panel |
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| EC50 | 211±n/a nM |
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| Citation |  PubChem, PC Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist Activity against Muscarinic Panel PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM44252 |
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| n/a |
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| Name | BDBM44252 |
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| Synonyms: | 4-[2-[(3,4-difluorobenzoyl)amino]ethylamino]piperidine-1-carboxylic acid ethyl ester;2,2,2-trifluoroacetic acid | 4-[2-[[(3,4-difluorophenyl)-oxomethyl]amino]ethylamino]-1-piperidinecarboxylic acid ethyl ester;2,2,2-trifluoroacetic acid | VU0359998 | cid_25010834 | ethyl 4-[2-[(3,4-difluorobenzoyl)amino]ethylamino]piperidine-1-carboxylate;2,2,2-trifluoroacetic acid | ethyl 4-[2-[[3,4-bis(fluoranyl)phenyl]carbonylamino]ethylamino]piperidine-1-carboxylate;2,2,2-tris(fluoranyl)ethanoic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23F2N3O3 |
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| Mol. Mass. | 355.3796 |
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| SMILES | CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccc(F)c(F)c1 |
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| Structure | 
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