| Reaction Details |
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 | Report a problem with these data |
| Target | Ephrin type-A receptor 4 |
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| Ligand | BDBM31698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists |
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| IC50 | 8980±n/a nM |
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| Citation |  PubChem, PC Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ephrin type-A receptor 4 |
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| Name: | Ephrin type-A receptor 4 |
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| Synonyms: | EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109812.17 |
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| Organism: | Mus musculus |
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| Description: | gi_34328113 |
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| Residue: | 986 |
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| Sequence: | MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVS
KYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNT
ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAIT
HQNKILSSVQAMRTQMQQMHGRMVPV
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| BDBM31698 |
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| n/a |
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| Name | BDBM31698 |
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| Synonyms: | 3-bromanyl-5-(3,3-dimethylpiperidin-1-yl)carbonyl-pyran-2-one | 3-bromo-5-(3,3-dimethylpiperidine-1-carbonyl)pyran-2-one | 3-bromo-5-[(3,3-dimethyl-1-piperidinyl)-oxomethyl]-2-pyranone | MLS000080954 | SMR000044848 | cid_664033 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16BrNO3 |
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| Mol. Mass. | 314.175 |
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| SMILES | CC1(C)CCCN(C1)C(=O)c1coc(=O)c(Br)c1 |
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| Structure | 
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