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Reaction Details
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TargetProtein Rev [8-24]
LigandBDBM44535
Substrate/Competitorn/a
Meas. Tech.Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50>79370±n/a nM
Citation PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Protein Rev [8-24]
Name:Protein Rev [8-24]
Synonyms:Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:Enzyme Catalytic Domain
Mol. Mass.:2446.81
Organism:Human immunodeficiency virus 1
Description:gi_253722402
Residue:17
Sequence:
TRQARRNRRRRWRERQR
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BDBM44535
n/a
NameBDBM44535
Synonyms:4-Dimethylaminomethyl-5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylic acid ethyl ester | 4-[(dimethylamino)methyl]-5-hydroxy-1,2-dimethyl-3-indolecarboxylic acid ethyl ester;oxalic acid | 4-[(dimethylamino)methyl]-5-hydroxy-1,2-dimethyl-indole-3-carboxylic acid ethyl ester;oxalic acid | MLS000076508 | SMR000012717 | cid_649608 | ethanedioic acid;ethyl 4-[(dimethylamino)methyl]-1,2-dimethyl-5-oxidanyl-indole-3-carboxylate | ethyl 4-[(dimethylamino)methyl]-5-hydroxy-1,2-dimethylindole-3-carboxylate;oxalic acid
TypeSmall organic molecule
Emp. Form.C16H22N2O3
Mol. Mass.290.3575
SMILESCCOC(=O)c1c(C)n(C)c2ccc(O)c(CN(C)C)c12
Structure
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