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TargetHematopoietic protein-tyrosine phosphatase (HEPTP)
LigandBDBM46189
Substrate/Competitorn/a
Meas. Tech.Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50 278±n/a nM
Citation PubChem PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hematopoietic protein-tyrosine phosphatase (HEPTP)
Name:Hematopoietic protein-tyrosine phosphatase (HEPTP)
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM46189
n/a
NameBDBM46189
Synonyms:1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-(2-methoxyethyl)urea | 1-[2,3-bis(2-furyl)quinoxalin-6-yl]-3-(2-methoxyethyl)urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-(2-methoxyethyl)urea | MLS-0202055.0001 | cid_3157647
TypeSmall organic molecule
Emp. Form.C20H18N4O4
Mol. Mass.378.3813
SMILESCOCCNC(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: