Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM46210 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP |
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IC50 | 8460±n/a nM |
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Citation | PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM46210 |
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n/a |
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Name | BDBM46210 |
Synonyms: | 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-sulfamoylphenyl)-1-piperazinecarbothioamide | 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide | 4-piperonyl-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide | MLS-0271926.0001 | cid_1213466 |
Type | Small organic molecule |
Emp. Form. | C19H22N4O4S2 |
Mol. Mass. | 434.532 |
SMILES | NS(=O)(=O)c1ccc(NC(=S)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 |
Structure |
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