Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM46273 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP |
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IC50 | 440±n/a nM |
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Citation | PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM46273 |
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n/a |
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Name | BDBM46273 |
Synonyms: | 2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-ylamino)-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]phenoxy]ethanoic acid | 2-[2-chloro-6-ethoxy-4-[(E)-[2-(2-naphthalenylamino)-4-oxo-5-thiazolylidene]methyl]phenoxy]acetic acid | 2-[2-chloro-6-ethoxy-4-[(E)-[2-(naphthalen-2-ylamino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenoxy]acetic acid | 2-[2-chloro-6-ethoxy-4-[(E)-[4-keto-2-(2-naphthylamino)-2-thiazolin-5-ylidene]methyl]phenoxy]acetic acid | MLS-0425588.0001 | cid_1228861 |
Type | Small organic molecule |
Emp. Form. | C24H19ClN2O5S |
Mol. Mass. | 482.936 |
SMILES | CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| |
Structure |
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