| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
|---|
| Ligand | BDBM32280 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. |
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| EC50 | 3970±n/a nM |
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| Citation |  PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 2 |
|---|
| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
|
|
|
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| BDBM32280 |
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| n/a |
|---|
| Name | BDBM32280 |
|---|
| Synonyms: | MLS000534769 | N-(4-acetylphenyl)-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-(4-acetylphenyl)-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-di-2-furyl-6-quinoxalinecarboxamide | N-(4-ethanoylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | SMR000142225 | cid_1331726 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H17N3O4 |
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| Mol. Mass. | 423.4202 |
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| SMILES | CC(=O)c1ccc(NC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1 |
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| Structure | 
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