| Reaction Details |
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 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
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| Ligand | BDBM46060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
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| IC50 | 1100±n/a nM |
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| Citation |  PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Mannose-6-phosphate isomerase |
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| Name: | Mannose-6-phosphate isomerase |
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| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46651.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448919 |
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| Residue: | 423 |
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| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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| BDBM46060 |
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| n/a |
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| Name | BDBM46060 |
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| Synonyms: | 2-(2,5-dimethylphenyl)-6-fluoranyl-1,2-benzothiazol-3-one | 2-(2,5-dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one | 727664-91-7 | MLS-0315771.0002 | MLS0315771 | cid_1510389 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12FNOS |
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| Mol. Mass. | 273.325 |
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| SMILES | Cc1ccc(C)c(c1)-n1sc2cc(F)ccc2c1=O |
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| Structure | 
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