| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mucolipin-3 |
|---|
| Ligand | BDBM46859 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) |
|---|
| EC50 | 3980±n/a nM |
|---|
| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mucolipin-3 |
|---|
| Name: | Mucolipin-3 |
|---|
| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 64244.09 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDD5 |
|---|
| Residue: | 553 |
|---|
| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
|
|
|
|---|
| BDBM46859 |
|---|
| n/a |
|---|
| Name | BDBM46859 |
|---|
| Synonyms: | (+)-BUTACLAMOL HYDROCHLORIDE | Butaclamol | MLS000028755 | SMR000058425 | cid_6852400 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H32ClNO |
|---|
| Mol. Mass. | 397.981 |
|---|
| SMILES | Cl.[H][C@@]12C[C@@](O)(CCN1C[C@@]1([H])c3ccccc3CCc3cccc2c13)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
