| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 8 |
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| Ligand | BDBM47703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 8 |
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| Name: | Regulator of G-protein signaling 8 |
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| Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20925.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_74355113 |
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| Residue: | 180 |
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| Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
|
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| BDBM47703 |
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| n/a |
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| Name | BDBM47703 |
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| Synonyms: | 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-(4-tert-butylanilino)-2-oxoethyl] ester | 2,3-dihydro-p-dioxin-5-carboxylic acid [2-(4-tert-butylanilino)-2-keto-ethyl] ester | MLS000082235 | SMR000061029 | [2-(4-tert-butylanilino)-2-oxoethyl] 2,3-dihydro-1,4-dioxine-5-carboxylate | [2-[(4-tert-butylphenyl)amino]-2-oxidanylidene-ethyl] 2,3-dihydro-1,4-dioxine-5-carboxylate | cid_2337962 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO5 |
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| Mol. Mass. | 319.3523 |
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| SMILES | CC(C)(C)c1ccc(NC(=O)COC(=O)C2=COCCO2)cc1 |t:15| |
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| Structure | 
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