| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 8 |
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| Ligand | BDBM34340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. |
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| EC50 | 12020±n/a nM |
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| Citation |  PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 8 |
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| Name: | Regulator of G-protein signaling 8 |
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| Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20925.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_74355113 |
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| Residue: | 180 |
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| Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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| BDBM34340 |
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| n/a |
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| Name | BDBM34340 |
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| Synonyms: | 2-(4-methyl-3-piperidin-1-ylsulfonyl-phenyl)-1,2-benzothiazol-3-one | 2-(4-methyl-3-piperidin-1-ylsulfonylphenyl)-1,2-benzothiazol-3-one | 2-(4-methyl-3-piperidinosulfonyl-phenyl)-1,2-benzothiazol-3-one | 2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one | MLS000057572 | SMR000060796 | cid_2327953 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O3S2 |
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| Mol. Mass. | 388.504 |
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| SMILES | Cc1ccc(cc1S(=O)(=O)N1CCCCC1)-n1sc2ccccc2c1=O |
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| Structure | 
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