Reaction Details |
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Target | Regulator of G-protein signaling 8 |
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Ligand | BDBM47710 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. |
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EC50 | >30000±n/a nM |
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Citation | PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 8 |
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Name: | Regulator of G-protein signaling 8 |
Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 20925.80 |
Organism: | Homo sapiens (Human) |
Description: | gi_74355113 |
Residue: | 180 |
Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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BDBM47710 |
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n/a |
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Name | BDBM47710 |
Synonyms: | (5-methyl-1,2-oxazol-3-yl)-[4-(2-phenylethyl)piperazin-1-yl]methanone | (5-methyl-3-isoxazolyl)-[4-(2-phenylethyl)-1-piperazinyl]methanone | (5-methylisoxazol-3-yl)-(4-phenethylpiperazino)methanone | 1-[(5-methyl-3-isoxazolyl)carbonyl]-4-(2-phenylethyl)piperazine | MLS000099809 | SMR000080791 | cid_1247515 |
Type | Small organic molecule |
Emp. Form. | C17H21N3O2 |
Mol. Mass. | 299.3675 |
SMILES | Cc1cc(no1)C(=O)N1CCN(CCc2ccccc2)CC1 |
Structure |
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