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TargetRegulator of G-protein signaling 8
LigandBDBM47712
Substrate/Competitorn/a
Meas. Tech.Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50>30000±n/a nM
Citation PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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  Blast E-value cutoff:
BDBM47712
n/a
NameBDBM47712
Synonyms:4-bromanyl-2-[[(1-methylbenzimidazol-2-yl)amino]methyl]phenol | 4-bromo-2-[[(1-methyl-2-benzimidazolyl)amino]methyl]phenol | 4-bromo-2-[[(1-methylbenzimidazol-2-yl)amino]methyl]phenol | MLS000110519 | SMR000106448 | cid_715151
TypeSmall organic molecule
Emp. Form.C15H14BrN3O
Mol. Mass.332.195
SMILESCn1c(NCc2cc(Br)ccc2O)nc2ccccc12
Structure
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