| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 8 |
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| Ligand | BDBM47776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. |
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| EC50 | 2610±n/a nM |
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| Citation |  PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 8 |
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| Name: | Regulator of G-protein signaling 8 |
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| Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20925.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_74355113 |
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| Residue: | 180 |
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| Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
|
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|
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| BDBM47776 |
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| n/a |
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| Name | BDBM47776 |
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| Synonyms: | 3-chloranyl-N-(3-morpholin-4-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-morpholin-4-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-morpholinopropyl)-6-nitro-benzothiophene-2-carboxamide | 3-chloro-N-[3-(4-morpholinyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide | MLS000684370 | SMR000295947 | cid_2225472 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18ClN3O4S |
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| Mol. Mass. | 383.85 |
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| SMILES | [O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)NCCCN1CCOCC1 |
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| Structure | 
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