| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 7 |
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| Ligand | BDBM47693 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 7 |
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| Name: | Regulator of G-protein signaling 7 |
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| Synonyms: | RGS7 | RGS7_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57675.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49802 |
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| Residue: | 495 |
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| Sequence: | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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| BDBM47693 |
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| n/a |
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| Name | BDBM47693 |
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| Synonyms: | 1-[3-(2-Chloro-6-fluoro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-piperidin-4-ol | 1-[3-(2-chloro-6-fluoro-benzyl)triazolo[4,5-d]pyrimidin-7-yl]piperidin-4-ol | 1-[3-[(2-chloranyl-6-fluoranyl-phenyl)methyl]-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperidin-4-ol | 1-[3-[(2-chloro-6-fluorophenyl)methyl]-7-triazolo[4,5-d]pyrimidinyl]-4-piperidinol | 1-[3-[(2-chloro-6-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]piperidin-4-ol | MLS000075681 | SMR000000498 | cid_644683 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16ClFN6O |
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| Mol. Mass. | 362.789 |
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| SMILES | OC1CCN(CC1)c1ncnc2n(Cc3c(F)cccc3Cl)nnc12 |
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| Structure | 
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