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Reaction Details
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TargetRGS7
LigandBDBM47708
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50>30000±n/a nM
Citation PubChem PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
RGS7
Name:RGS7
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:57675.72
Organism:Homo sapiens (Human)
Description:P49802
Residue:495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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  Blast E-value cutoff:
BDBM47708
n/a
NameBDBM47708
Synonyms:1-(4-chlorobenzyl)sulfonylisonipecotic acid ethyl ester | 1-[(4-chlorophenyl)methylsulfonyl]-4-piperidinecarboxylic acid ethyl ester | MLS000066348 | SMR000081233 | cid_2228514 | ethyl 1-[(4-chlorobenzyl)sulfonyl]-4-piperidinecarboxylate | ethyl 1-[(4-chlorophenyl)methylsulfonyl]piperidine-4-carboxylate
TypeSmall organic molecule
Emp. Form.C15H20ClNO4S
Mol. Mass.345.842
SMILESCCOC(=O)C1CCN(CC1)S(=O)(=O)Cc1ccc(Cl)cc1
Structure
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