| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Regulator of G-protein signaling 19 |
|---|
| Ligand | BDBM34524 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. |
|---|
| EC50 | 1350±n/a nM |
|---|
| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Regulator of G-protein signaling 19 |
|---|
| Name: | Regulator of G-protein signaling 19 |
|---|
| Synonyms: | G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19) |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 24631.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_86990435 |
|---|
| Residue: | 217 |
|---|
| Sequence: | MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
|
|
|
|---|
| BDBM34524 |
|---|
| n/a |
|---|
| Name | BDBM34524 |
|---|
| Synonyms: | 2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-4,6-dimethyl-isothiazolo[5,4-b]pyridin-3-one | 4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-3-isothiazolo[5,4-b]pyridinone | 4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-[1,2]thiazolo[5,4-b]pyridin-3-one | 4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-[1,2]thiazolo[5,4-b]pyridin-3-one | MLS000118900 | SMR000095840 | cid_5309798 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N4O2S |
|---|
| Mol. Mass. | 410.532 |
|---|
| SMILES | CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
