Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 19

Ligand

BDBM47718

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 19

Name:

Regulator of G-protein signaling 19

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

24631.38

Organism:

Homo sapiens (Human)

Description:

gi_86990435

Residue:

217

Sequence:

MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA

BDBM47718

n/a

Name

BDBM47718

Synonyms:

2-[4-(3-Cyclohexyl-ureido)-phenyl]-3,3,3-trifluoro-2-hydroxy-propionic acid methyl ester | 2-[4-(cyclohexylcarbamoylamino)phenyl]-3,3,3-trifluoro-2-hydroxy-propionic acid methyl ester | 2-[4-[[(cyclohexylamino)-oxomethyl]amino]phenyl]-3,3,3-trifluoro-2-hydroxypropanoic acid methyl ester | MLS000554163 | SMR000146480 | cid_3767936 | methyl 2-[4-(cyclohexylcarbamoylamino)phenyl]-3,3,3-trifluoro-2-hydroxypropanoate | methyl 2-[4-(cyclohexylcarbamoylamino)phenyl]-3,3,3-tris(fluoranyl)-2-oxidanyl-propanoate

Type

Small organic molecule

Emp. Form.

C17H21F3N2O4

Mol. Mass.

374.3548

SMILES

COC(=O)C(O)(c1ccc(NC(=O)NC2CCCCC2)cc1)C(F)(F)F

Structure