Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 16

Ligand

BDBM47695

Substrate/Competitor

n/a

Meas. Tech.

Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 16

Name:

Regulator of G-protein signaling 16

Synonyms:

RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16

Type:

Enzyme Catalytic Domain

Mol. Mass.:

22748.87

Organism:

Homo sapiens (Human)

Description:

gi_156416009

Residue:

202

Sequence:

MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT

BDBM47695

n/a

Name

BDBM47695

Synonyms:

2-(N-[2-(1-benzotriazolyl)-1-oxoethyl]-2-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methyl-2-pyrrolyl)acetamide | 2-(N-[2-(benzotriazol-1-yl)acetyl]-2-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methylpyrrol-2-yl)acetamide | 2-[(2-Benzotriazol-1-yl-acetyl)-(2-methoxy-phenyl)-amino]-N-(1,1-dimethyl-propyl)-2-(1-methyl-1H-pyrrol-2-yl)-acetamide | 2-[2-(benzotriazol-1-yl)ethanoyl-(2-methoxyphenyl)amino]-N-(2-methylbutan-2-yl)-2-(1-methylpyrrol-2-yl)ethanamide | MLS000074185 | N-tert-amyl-2-(N-[2-(benzotriazol-1-yl)acetyl]-2-methoxy-anilino)-2-(1-methylpyrrol-2-yl)acetamide | SMR000004342 | cid_646963

Type

Small organic molecule

Emp. Form.

C27H32N6O3

Mol. Mass.

488.5814

SMILES

CCC(C)(C)NC(=O)C(N(C(=O)Cn1nnc2ccccc12)c1ccccc1OC)c1cccn1C

Structure