Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 16

Ligand

BDBM47766

Substrate/Competitor

n/a

Meas. Tech.

Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 16

Name:

Regulator of G-protein signaling 16

Synonyms:

RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16

Type:

Enzyme Catalytic Domain

Mol. Mass.:

22748.87

Organism:

Homo sapiens (Human)

Description:

gi_156416009

Residue:

202

Sequence:

MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT

BDBM47766

n/a

Name

BDBM47766

Synonyms:

MLS000676949 | N-[(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)carbamothioyl]cyclohexanecarboxamide | N-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamothioyl]cyclohexanecarboxamide | N-[(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)thiocarbamoyl]cyclohexanecarboxamide | N-[[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-sulfanylidenemethyl]cyclohexanecarboxamide | N-{[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]carbonothioyl}cyclohexanecarboxamide | SMR000271138 | cid_1327665

Type

Small organic molecule

Emp. Form.

C19H24N4O2S

Mol. Mass.

372.484

SMILES

Cc1c(NC(=S)NC(=O)C2CCCCC2)c(=O)n(-c2ccccc2)n1C

Structure