| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
|---|
| Ligand | BDBM32909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 3341±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
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| BDBM32909 |
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| n/a |
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| Name | BDBM32909 |
|---|
| Synonyms: | (4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-carboxylate | (4-methyl-2-oxochromen-7-yl) furan-2-carboxylate | 2-furancarboxylic acid (4-methyl-2-oxo-1-benzopyran-7-yl) ester | MLS000712758 | SMR000282525 | US11584714, Compound 12# | cid_728528 | furan-2-carboxylic acid (2-keto-4-methyl-chromen-7-yl) ester |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C15H10O5 |
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| Mol. Mass. | 270.2369 |
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| SMILES | Cc1cc(=O)oc2cc(OC(=O)c3ccco3)ccc12 |
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| Structure | 
|
|---|
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