| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
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| Ligand | BDBM47870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 4586±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
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|
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| BDBM47870 |
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| n/a |
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| Name | BDBM47870 |
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| Synonyms: | 2-chloranyl-1-[2,5-dimethyl-1-(3-nitrophenyl)pyrrol-3-yl]ethanone | 2-chloro-1-[2,5-dimethyl-1-(3-nitrophenyl)-3-pyrrolyl]ethanone | 2-chloro-1-[2,5-dimethyl-1-(3-nitrophenyl)pyrrol-3-yl]ethanone | MLS000877947 | SMR000376939 | cid_2526861 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C14H13ClN2O3 |
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| Mol. Mass. | 292.718 |
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| SMILES | Cc1cc(C(=O)CCl)c(C)n1-c1cccc(c1)[N+]([O-])=O |
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| Structure | 
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