Reaction Details |
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Target | 3C-like protease |
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Ligand | BDBM47871 |
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Substrate/Competitor | n/a |
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Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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IC50 | 5098±n/a nM |
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Citation | PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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3C-like protease |
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Name: | 3C-like protease |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 33462.05 |
Organism: | Avian infectious bronchitis virus |
Description: | gi_73745819 |
Residue: | 307 |
Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47871 |
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n/a |
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Name | BDBM47871 |
Synonyms: | 4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]carbonyl-1H-quinolin-2-one | 4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one | 4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]carbostyril | 4-[oxo-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]methyl]-1H-quinolin-2-one | CVD-0013258 | ERI-UCB-a0b0dbcb-4 | MLS000760808 | SMR000370919 | cid_2449860 |
Type | Small organic molecule |
Emp. Form. | C21H18F3N3O2 |
Mol. Mass. | 401.3817 |
SMILES | FC(F)(F)c1cccc(c1)N1CCN(CC1)C(=O)c1cc(=O)[nH]c2ccccc12 |
Structure |
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