Reaction Details |
| Report a problem with these data |
Target | 3C-like protease |
---|
Ligand | BDBM47546 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
---|
IC50 | 5219±n/a nM |
---|
Citation | PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
3C-like protease |
---|
Name: | 3C-like protease |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 33462.05 |
Organism: | Avian infectious bronchitis virus |
Description: | gi_73745819 |
Residue: | 307 |
Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
BDBM47546 |
---|
n/a |
---|
Name | BDBM47546 |
Synonyms: | 2-[[(E)-1-oxo-3-thiophen-2-ylprop-2-enyl]amino]-4-phenyl-3-thiophenecarboxylic acid | 4-phenyl-2-[[(E)-3-(2-thienyl)acryloyl]amino]-3-thenoic acid | 4-phenyl-2-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]thiophene-3-carboxylic acid | MLS000773385 | SMR000364116 | cid_1177253 |
Type | Small organic molecule |
Emp. Form. | C18H13NO3S2 |
Mol. Mass. | 355.431 |
SMILES | OC(=O)c1c(NC(=O)\C=C\c2cccs2)scc1-c1ccccc1 |
Structure |
|