Reaction Details |
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Target | 3C-like protease |
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Ligand | BDBM47905 |
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Substrate/Competitor | n/a |
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Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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IC50 | 5195±n/a nM |
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Citation | PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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3C-like protease |
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Name: | 3C-like protease |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 33462.05 |
Organism: | Avian infectious bronchitis virus |
Description: | gi_73745819 |
Residue: | 307 |
Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47905 |
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n/a |
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Name | BDBM47905 |
Synonyms: | 2-chloranyl-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(2-furanyl)-5-(5-methyl-2-furanyl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[5-(2-furyl)-3-(5-methyl-2-furyl)-2-pyrazolin-1-yl]ethanone | MLS001179882 | SMR000595582 | cid_4961646 |
Type | Small organic molecule |
Emp. Form. | C14H13ClN2O3 |
Mol. Mass. | 292.718 |
SMILES | Cc1ccc(o1)C1=NN(C(C1)c1ccco1)C(=O)CCl |t:7| |
Structure |
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