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Target3C-like protease
LigandBDBM47905
Substrate/Competitorn/a
Meas. Tech.QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50 5195±n/a nM
Citation PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
3C-like protease
Name:3C-like protease
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:33462.05
Organism:Avian infectious bronchitis virus
Description:gi_73745819
Residue:307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47905
n/a
NameBDBM47905
Synonyms:2-chloranyl-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(2-furanyl)-5-(5-methyl-2-furanyl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[5-(2-furyl)-3-(5-methyl-2-furyl)-2-pyrazolin-1-yl]ethanone | MLS001179882 | SMR000595582 | cid_4961646
TypeSmall organic molecule
Emp. Form.C14H13ClN2O3
Mol. Mass.292.718
SMILESCc1ccc(o1)C1=NN(C(C1)c1ccco1)C(=O)CCl |t:7|
Structure
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