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Target3C-like protease
LigandBDBM47913
Substrate/Competitorn/a
Meas. Tech.QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50 7068±n/a nM
Citation PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
3C-like protease
Name:3C-like protease
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:33462.05
Organism:Avian infectious bronchitis virus
Description:gi_73745819
Residue:307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47913
n/a
NameBDBM47913
Synonyms:MLS001030320 | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-(2-pyridinylthio)acetamide | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanyl-ethanamide | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide | N-(4-nitrofurazan-3-yl)-2-(2-pyridylthio)acetamide | SMR000635635 | cid_4917203
TypeSmall organic molecule
Emp. Form.C9H7N5O4S
Mol. Mass.281.248
SMILES[O-][N+](=O)c1nonc1NC(=O)CSc1ccccn1
Structure
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