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Target3C-like protease
LigandBDBM47921
Substrate/Competitorn/a
Meas. Tech.QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50 5926±n/a nM
Citation PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
3C-like protease
Name:3C-like protease
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:33462.05
Organism:Avian infectious bronchitis virus
Description:gi_73745819
Residue:307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47921
n/a
NameBDBM47921
Synonyms:Furan-2-carboxylic acid (cyclopentylcarbamoyl-pyridin-3-yl-methyl)-(4-isopropyl-phenyl)-amide | MLS001222475 | N-[2-(cyclopentylamino)-2-keto-1-(3-pyridyl)ethyl]-N-p-cumenyl-2-furamide | N-[2-(cyclopentylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide | N-[2-(cyclopentylamino)-2-oxo-1-(3-pyridinyl)ethyl]-N-(4-propan-2-ylphenyl)-2-furancarboxamide | N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide | SMR000600356 | cid_3196509
TypeSmall organic molecule
Emp. Form.C26H29N3O3
Mol. Mass.431.5268
SMILESCC(C)c1ccc(cc1)N(C(C(=O)NC1CCCC1)c1cccnc1)C(=O)c1ccco1
Structure
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