Reaction Details |
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Target | 3C-like protease |
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Ligand | BDBM47921 |
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Substrate/Competitor | n/a |
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Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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IC50 | 5926±n/a nM |
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Citation | PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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3C-like protease |
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Name: | 3C-like protease |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 33462.05 |
Organism: | Avian infectious bronchitis virus |
Description: | gi_73745819 |
Residue: | 307 |
Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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BDBM47921 |
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n/a |
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Name | BDBM47921 |
Synonyms: | Furan-2-carboxylic acid (cyclopentylcarbamoyl-pyridin-3-yl-methyl)-(4-isopropyl-phenyl)-amide | MLS001222475 | N-[2-(cyclopentylamino)-2-keto-1-(3-pyridyl)ethyl]-N-p-cumenyl-2-furamide | N-[2-(cyclopentylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide | N-[2-(cyclopentylamino)-2-oxo-1-(3-pyridinyl)ethyl]-N-(4-propan-2-ylphenyl)-2-furancarboxamide | N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide | SMR000600356 | cid_3196509 |
Type | Small organic molecule |
Emp. Form. | C26H29N3O3 |
Mol. Mass. | 431.5268 |
SMILES | CC(C)c1ccc(cc1)N(C(C(=O)NC1CCCC1)c1cccnc1)C(=O)c1ccco1 |
Structure |
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