| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock protein HSP 90-alpha |
|---|
| Ligand | BDBM33185 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence-based dose response biochemical high throughput screening assay for inhibitors of the Heat Shock Protein 90 (HSP90) |
|---|
| IC50 | 967±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based dose response biochemical high throughput screening assay for inhibitors of the Heat Shock Protein 90 (HSP90) PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock protein HSP 90-alpha |
|---|
| Name: | Heat shock protein HSP 90-alpha |
|---|
| Synonyms: | HS90A_HUMAN | HSP 86 | HSP86 | HSP90A | HSP90AA1 | HSPC1 | HSPCA | Heat Shock Protein 90 (Hsp90) | Heat shock 86 kDa | Heat shock protein HSP 90 (HSP90) | Heat shock protein HSP 90-alpha (HSP90) | Heat shock protein HSP 90-alpha (HSP90A) | LAP-2 | LPS-associated protein 2 | Lipopolysaccharide-associated protein 2 | Renal carcinoma antigen NY-REN-38 | heat shock protein 90kDa alpha (cytosolic), class A member 1 isoform 2 |
|---|
| Type: | Molecular Chaperone |
|---|
| Mol. Mass.: | 84623.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07900 |
|---|
| Residue: | 732 |
|---|
| Sequence: | MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR
YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME
ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM
GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED
KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN
PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN
IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC
LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY
CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT
LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV
TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK
DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE
GDDDTSRMEEVD
|
|
|
|---|
| BDBM33185 |
|---|
| n/a |
|---|
| Name | BDBM33185 |
|---|
| Synonyms: | 4-({(4Z)-1-oxo-4-[(phenylsulfonyl)imino]-1,4-dihydronaphthalen-2-yl}amino)benzoic acid | 4-[(4-besylimino-1-keto-2-naphthyl)amino]benzoic acid | 4-[[(4Z)-4-besylimino-1-keto-2-naphthyl]amino]benzoic acid | 4-[[1-oxidanylidene-4-(phenylsulfonylimino)naphthalen-2-yl]amino]benzoic acid | 4-[[4-(benzenesulfonylimino)-1-oxo-2-naphthalenyl]amino]benzoic acid | 4-[[4-(benzenesulfonylimino)-1-oxonaphthalen-2-yl]amino]benzoic acid | MLS000686314 | SMR000313157 | cid_4053104 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H16N2O5S |
|---|
| Mol. Mass. | 432.449 |
|---|
| SMILES | OC(=O)c1ccc(NC2=CC(=NS(=O)(=O)c3ccccc3)c3ccccc3C2=O)cc1 |w:11.11,t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
