| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transcription factor p65 |
|---|
| Ligand | BDBM21625 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response |
|---|
| EC50 | 2322±n/a nM |
|---|
| Citation |  PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Transcription factor p65 |
|---|
| Name: | Transcription factor p65 |
|---|
| Synonyms: | NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 60211.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q04206 |
|---|
| Residue: | 551 |
|---|
| Sequence: | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
|
|
|
|---|
| BDBM21625 |
|---|
| n/a |
|---|
| Name | BDBM21625 |
|---|
| Synonyms: | 2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole | 2-phenyl-5-(1H-pyrazol-5-yl)thiazole | Pyrazolylthiazole, 13 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H9N3S |
|---|
| Mol. Mass. | 227.285 |
|---|
| SMILES | c1cc(n[nH]1)-c1cnc(s1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
