Reaction Details |
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Target | Induced myeloid leukemia cell differentiation protein Mcl-1 |
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Ligand | BDBM50028 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors |
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IC50 | 433.417842±n/a nM |
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Citation | PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Induced myeloid leukemia cell differentiation protein Mcl-1 |
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Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 |
Synonyms: | BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT |
Type: | Membrane; Single-pass membrane protein |
Mol. Mass.: | 37332.87 |
Organism: | Homo sapiens (Human) |
Description: | Q07820 |
Residue: | 350 |
Sequence: | MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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BDBM50028 |
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n/a |
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Name | BDBM50028 |
Synonyms: | 4-[2-[2-[butyl(ethyl)amino]ethylamino]-3,4-diketo-cyclobuten-1-yl]piperazine-1-carboxylic acid ethyl ester | 4-[2-[2-[butyl(ethyl)amino]ethylamino]-3,4-dioxo-1-cyclobutenyl]-1-piperazinecarboxylic acid ethyl ester | MLS000093371 | SMR000028989 | cid_3235628 | ethyl 4-[2-({2-[butyl(ethyl)amino]ethyl}amino)-3,4-dioxocyclobut-1-en-1-yl]piperazine-1-carboxylate | ethyl 4-[2-[2-[butyl(ethyl)amino]ethylamino]-3,4-bis(oxidanylidene)cyclobuten-1-yl]piperazine-1-carboxylate | ethyl 4-[2-[2-[butyl(ethyl)amino]ethylamino]-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxylate |
Type | Small organic molecule |
Emp. Form. | C19H32N4O4 |
Mol. Mass. | 380.4818 |
SMILES | CCCCN(CC)CCNc1c(N2CCN(CC2)C(=O)OCC)c(=O)c1=O |
Structure |
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