| Reaction Details |
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 | Report a problem with these data |
| Target | Induced myeloid leukemia cell differentiation protein Mcl-1 |
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| Ligand | BDBM50357 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors |
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| IC50 | 400±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Induced myeloid leukemia cell differentiation protein Mcl-1 |
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| Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 |
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| Synonyms: | BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT |
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| Type: | Membrane; Single-pass membrane protein |
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| Mol. Mass.: | 37332.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q07820 |
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| Residue: | 350 |
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| Sequence: | MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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| BDBM50357 |
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| n/a |
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| Name | BDBM50357 |
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| Synonyms: | 3-(1-phenyl-2-benzimidazolyl)propanoic acid [2-[4-[ethyl(propan-2-yl)amino]anilino]-2-oxoethyl] ester | 3-(1-phenylbenzimidazol-2-yl)propionic acid [2-[4-[ethyl(isopropyl)amino]anilino]-2-keto-ethyl] ester | MLS000389419 | SMR000255692 | [2-[4-[ethyl(propan-2-yl)amino]anilino]-2-oxoethyl] 3-(1-phenylbenzimidazol-2-yl)propanoate | [2-[[4-[ethyl(propan-2-yl)amino]phenyl]amino]-2-oxidanylidene-ethyl] 3-(1-phenylbenzimidazol-2-yl)propanoate | cid_4619852 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H32N4O3 |
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| Mol. Mass. | 484.5894 |
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| SMILES | CCN(C(C)C)c1ccc(NC(=O)COC(=O)CCc2nc3ccccc3n2-c2ccccc2)cc1 |
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| Structure | 
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