| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase Mdm2 |
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| Ligand | BDBM43477 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | E3 Ligase_Mutant_Dose Response |
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| EC50 | 580±n/a nM |
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| Citation |  PubChem, PC E3 Ligase_Mutant_Dose Response PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| E3 ubiquitin-protein ligase Mdm2 |
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| Name: | E3 ubiquitin-protein ligase Mdm2 |
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| Synonyms: | Double minute 2 protein | Double minute 2 protein (HDM2) | E3 ubiquitin-protein ligase Mdm2 (p53-binding protein Mdm2) | Hdm2 | Human Double Minute 2 (HDM2) | MDM2 | MDM2-MDMX | MDM2_HUMAN | p53-Binding Protein MDM2 | p53-binding protein |
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| Type: | Oncoprotein |
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| Mol. Mass.: | 55196.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q00987 |
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| Residue: | 491 |
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| Sequence: | MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS
VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLA
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP
DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ
DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
PIQMIVLTYFP
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| BDBM43477 |
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| n/a |
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| Name | BDBM43477 |
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| Synonyms: | 1,4-Pentadien-3-one, 1,5-di-3-pyridyl- | 1,5-bis(3-pyridinyl)-3-penta-1,4-dienone | 1,5-bis(3-pyridyl)penta-1,4-dien-3-one | 1,5-dipyridin-3-ylpenta-1,4-dien-3-one | MLS000766145 | SMR000528628 | cid_288321 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2O |
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| Mol. Mass. | 236.2686 |
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| SMILES | O=C(C=Cc1cccnc1)C=Cc1cccnc1 |
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| Structure | 
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