Reaction Details |
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Target | Regulator of G-protein signaling 4 |
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Ligand | BDBM47705 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. |
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EC50 | 30000±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 4 |
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Name: | Regulator of G-protein signaling 4 |
Synonyms: | RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4) |
Type: | Enzyme |
Mol. Mass.: | 23263.51 |
Organism: | Homo sapiens (Human) |
Description: | P49798 |
Residue: | 205 |
Sequence: | MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA
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BDBM47705 |
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n/a |
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Name | BDBM47705 |
Synonyms: | 1-[2-(difluoromethoxy)-5-methyl-phenyl]-3-(2,4-dimethoxyphenyl)urea | 1-[2-(difluoromethoxy)-5-methylphenyl]-3-(2,4-dimethoxyphenyl)urea | 1-[2-[bis(fluoranyl)methoxy]-5-methyl-phenyl]-3-(2,4-dimethoxyphenyl)urea | MLS000097201 | N-[2-(difluoromethoxy)-5-methylphenyl]-N'-(2,4-dimethoxyphenyl)urea | SMR000076793 | cid_2208379 |
Type | Small organic molecule |
Emp. Form. | C17H18F2N2O4 |
Mol. Mass. | 352.3326 |
SMILES | COc1ccc(NC(=O)Nc2cc(C)ccc2OC(F)F)c(OC)c1 |
Structure |
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