| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM52009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase |
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| IC50 | 1977±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM52009 |
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| n/a |
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| Name | BDBM52009 |
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| Synonyms: | 5-Bromo-3-[2-(4-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-1H-indole-2-carboxylic acid | 5-bromanyl-3-[2-[4-nitro-1,3-bis(oxidanylidene)isoindol-2-yl]ethyl]-1H-indole-2-carboxylic acid | 5-bromo-3-[2-(1,3-diketo-4-nitro-isoindolin-2-yl)ethyl]-1H-indole-2-carboxylic acid | 5-bromo-3-[2-(4-nitro-1,3-dioxo-2-isoindolyl)ethyl]-1H-indole-2-carboxylic acid | 5-bromo-3-[2-(4-nitro-1,3-dioxoisoindol-2-yl)ethyl]-1H-indole-2-carboxylic acid | MLS000778197 | SMR000414882 | cid_1418929 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H12BrN3O6 |
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| Mol. Mass. | 458.219 |
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| SMILES | OC(=O)c1[nH]c2ccc(Br)cc2c1CCN1C(=O)c2cccc(c2C1=O)[N+]([O-])=O |
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| Structure | 
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